Can patients take Ibuprofen and Tylenol together Concomitant administration of ibuprofen in doses of 200 to 400 mg with Tylenol products is safe combination. There are also products on the market containing both, ibuprofen and acetaminophen in one dosage form, usually tablet. An Effectiveness and Safety Study of Acetaminophen 1000 mg and Ibuprofen 400 mg in Postoperative Dental Pain. Yes it is safe to take 600mg ibuprofen with 500mg acetaminophen at the same time. You can also do 800mg ibuprofen with it. The ER doctor used the combination on me. They say it's better than the You can also do 800mg ibuprofen with it. Take 1000mg of paracetamol every 4-6 hours Take 400mg of Ibuprofen every 8 hours (with food) If you want to take a higher dose, you must first speak to your doctor or pharmacist. Thank you for your reply. Ibuprofen Tablets, USP contain the active ingredient ibuprofen, which is (±)-2-(p-isobutylphenyl) propionic acid. Ibuprofen is a white powder with a melting point of 74° to 77° C and is very slightly soluble in water ( 1 mg/mL) and readily soluble in organic solvents such as ethanol and acetone. I have Ibuprofen tablets that are 400 mg each, and I usually take between 3–5 tablets every day. Is this dangerous? I’m supposed to avoid medications like ibuprofen because I have only one kidney and I am very underweight, but I seem to be relying on them more and more for pain relief. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Acharya on can i take 1600 mg of ibuprofen: That would be an overdose for this medication. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Acharya on can i take 1600 mg of ibuprofen: That would be an overdose for this medication. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Lessnau on 1000 mg ibuprofen: There are no interactions. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Lessnau on 1000 mg ibuprofen: There are no interactions..